The Abnormal Expression of MicroRNA-542-3p in Hepatocellular Carcinoma and Its Clinical Significance

Table 3

Association of miRNA-542-3p expression with clinicopathological parameters in HCC.

Clinical parameters		miRNA-542-3p relative expression (2^−ΔΔCt)
		Mean ± SD	t
Age
<50	24	0.829 ± 1.200	0.048	0.961
≥50	48	0.843 ± 1.213
Gender
Male	59	0.907 ± 1.218	1.026	0.308
Female	13	0.530 ± 1.101
AFP (ng/mL)
<400	33	0.854 ± 1.264	−0.102	0.919
≥400	39	0.825 ± 1.158
Cirrhosis
Negative	28	1.065 ± 1.289	−1.248	0.218
Positive	44	0.694 ± 1.130
Size (cm)
<10	29	1.362 ± 1.330	−3.047	0.004
≥10	43	0.485 ± 0.967
Differentiation
High	21	1.497 ± 1.379	−2.794	0.009
Low/moderate	51	0.567 ± 1.012
TNM stage
I-II	28	0.582 ± 1.056	1.459	0.149
III-IV	44	1.002 ± 1.267
HBV
Negative	25	0.623 ± 1.039	1.187	0.240
Positive	47	0.953 ± 1.272
Portal invasion
Negative	27	1.483 ± 1.351	−3.514	0.001
Positive	45	0.452 ± 0.914

Data are presented as mean ± SD. . .