Follistatin-Like 1 Is Downregulated in Morbidly and Super Obese Central-European Population
Table 1
Study participant characteristics.
Parameter
Unit
Obese
Nonobese
Total
value
81
52
133
Age
Years
52.5 ± 10.7
38.7 ± 10.8
47.1 ± 12.6
<0.001
Height
cm
166.4 ± 8.5
167.8 ± 8.9
166.9 ± 8.7
0.511
Weight
kg
124.1 ± 20.9
64.6 ± 10.8
100.8 ± 34.1
<0.001
BMI
kg/m2
44.8 ± 6.0
22.8 ± 2.3
36.1 ± 11.8
<0.001
Systolic blood pressure
mmHg
145.2 ± 19.5
116.4 ± 15.0
133.7 ± 22.7
<0.001
Diastolic blood pressure
mmHg
94.6 ± 13.0
77.3 ± 11.1
87.7 ± 14.9
<0.001
Triceptal skinfold thickness
mm
31.7 ± 6.4
18.0 ± 5.1
26.3 ± 9.0
<0.001
Biceptal skinfold thickness
mm
26.0 ± 8.0
11.3 ± 3.9
20.2 ± 9.8
<0.001
Supraspinal skinfold thickness
mm
32.1 ± 9.7
13.2 ± 4.2
24.3 ± 12.2
<0.001
Subscapular skinfold thickness
mm
35.4 ± 8.7
15.8 ± 4.8
27.6 ± 12.1
<0.001
Total body fat
%
49.1 ± 7.1
25.8 ± 7.2
40.0 ± 13.4
<0.001
Total body water
%
39.6 ± 5.1
54.2 ± 4.8
45.3 ± 8.7
<0.001
Hip circumference
cm
136.0 ± 12.4
97.6 ± 5.9
121.0 ± 21.4
<0.001
Waist circumference
cm
126.5 ± 13.5
77.8 ± 9.0
107.5 ± 26.7
<0.001
Hip-waist ratio
—
0.93 ± 0.10
0.80 ± 0.07
0.88 ± 0.11
<0.001
FSTL1
ng/mL
2.89 ± 1.18
4.83 ± 1.28
3.53 ± 1.15
0.044
FSTL1: genotype GG
ng/mL
2.69 ± 1.43
22.41 ± 1.97
5.24 ± 1.43
0.002
FSTL1: genotype GT
ng/mL
3.30 ± 1.25
2.76 ± 1.30
3.05 ± 1.18
0.998
FSTL1: genotype TT
ng/mL
2.89 ± 1.33
4.03 ± 1.56
3.24 ± 1.27
0.991
FSTL1 level is presented as a geometric mean ± geometric standard error of the mean; other parameters are presented as an arithmetic mean ± standard deviation.
