Clinical Significance of Hemostatic Parameters in the Prediction for Type 2 Diabetes Mellitus and Diabetic Nephropathy

Table 1

Clinical characteristics of controls and patients with type 2 diabetes mellitus.

	Controls	T2DM without complications	Diabetic nephropathy	value
	141	202	95
Systolic pressure (mmHg)	106 ± 10	107 ± 12	105 ± 12	>0.05
eGFR (mL/min)	75.3 ± 10.4	79.2 ± 13.2	95.6 ± 20.1	<0.01
WBC (g/L)	4.67 ± 1.01	5.12 ± 1.20	5.04 ± 1.30	>0.05
HGB (g/L)	120 ± 12	121 ± 13	118 ± 14	>0.05
RDW (%)	12.3 ± 1.1	12.9 ± 1.4	13.2 ± 1.5	<0.01
TSH (μmmol/L)	1.22 ± 0.51	1.44 ± 0.46	1.55 ± 0.49	<0.05
C-peptide (nmol/L)	0.61 ± 0.22	1.02 ± .031	1.21 ± 0.47	<0.01
HbA1c (%)	3.02 ± 1.33	6.22 ± 2.65	6.33 ± 2.56	<0.01
HDL (mmol/L)	1.01 ± 0.33	0.89 ± 0.35	0.77 ± 0.30	<0.01
CHOL (mmol/L)	2.35 ± 1.44	3.01 ± 1.69	3.43 ± 1.77	<0.01
ALB (g/L)	45.3 ± 12.1	42.4 ± 10.5	40.0 ± 11.2	<0.05

Data were presented as mean and standard deviation (SD) or median (range). T2DM: type 2 diabetes mellitus; eGFR: estimated glomerular filtration rate; WBC: white blood cell; HGB: hemoglobin; RDW: red cell distribution width; TSH: thyroid-stimulating hormone; HbA1c: glycosylated hemoglobin A1c; HDL: high-density lipoprotein; CHOL: cholesterol; ALB: albumin. value: comparisons of the three groups by one-way analysis of variance. compared with controls and patients with T2DM without complications; compared with controls.