Plasma Heme Oxygenase-1 Levels in Patients with Coronary and Peripheral Artery Diseases
Table 2
Clinical characteristics and plasma HO-1 levels of patients with and without PAD.
PAD(−) ()
PAD(+) ()
value
Age (years)
67 ± 11
73 ± 9
<0.002
Gender (male)
264 (71%)
27 (75%)
NS
BMI (kg/m2)
23.7 ± 4.0
22.7 ± 3.2
NS
Hypertension
262 (70%)
34 (94%)
<0.005
Systolic blood pressure (mmHg)
132 ± 20
131 ± 31
NS
Diabetes mellitus
92 (25%)
14 (39%)
NS
Smoking
138 (37%)
20 (56%)
<0.05
Hyperlipidemia
181 (48%)
25 (69%)
<0.05
Statin
128 (34%)
23 (64%)
<0.001
LDL-cholesterol (mg/dL)
113 ± 31
115 ± 31
NS
HDL-cholesterol (mg/dL)
55 ± 15
48 ± 11
<0.01
HO-1 levels (ng/mL)
0.41 [0.26, 0.57]
0.27 [0.18, 0.45]
<0.02
HO-1 < 0.35 ng/mL
158 (42%)
22 (61%)
<0.05
CAD
192 (51%)
33 (92%)
<0.001
1-VD
82 (22%)
9 (25%)
NS
2-VD
61 (16%)
5 (14%)
NS
3-VD
48 (13%)
19 (53%)
<0.001
Aspirin
165 (44%)
24 (67%)
<0.025
Data represent the mean ± SD or the number (%) of patients, with the exception of HO-1 level which is presented as the median value and interquartile range.
