Research Article

Circulating Heat Shock Protein 70 Is a Novel Biomarker for Early Diagnosis of Lung Cancer

Table 3

The diagnostic efficiency of model in NSCLC and controls.

AUC (95% CI)SN (%)SP (%)Positive LRNegative LR

NSCLC versus control
 HSP70 + CEA + CA 19-90.945 (0.855–1.000)75.01000.25
 HSP700.898 (0.764–1.000)75.093.812.10.27
 CEA + CA 19-90.844 (0.687–1.000)10062.52.70
 CEA0.836 (0.672–1.000)87.581.34.70.28
 CA 19-90.773 (0.565–0.982)75.068.82.40.36