Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention

Table 2

Univariate and multivariate analyses of the relationship between uric acid and all-cause mortality.

	Univariate analysis			Multivariate analyses
	HR	95% CI	value	HR	95% CI	value
Sex	0.68	(0.49, 0.93)	0.017	0.73	(0.54, 0.85)	0.012
Age	1.09	(1.07, 1.11)	<0.001	1.11	(1.09, 1.14)	<0.001
History of heart failure	3.12	(2.16, 4.50)	<0.001	3.10	(2.15, 4.47)	<0.001
History of atrial fibrillation	2.68	(1.23, 5.83)	0.013	2.65	(1.22, 5.78)	0.014
History of stroke	1.40	(0.75, 2.59)	0.287	—	—	—
History of PCI	0.70	(0.34, 1.46)	0.346	—	—	—
History of hypertension	1.04	(0.76, 1.42)	0.807	—	—	—
History of diabetes	2.13	(1.53, 2.98)	<0.001	2.17	(1.55, 3.04)	<0.001
Smoking	0.97	(0.69, 1.35)	0.841	—	—	—
BMI	0.92	(0.88, 1.09)	0.215	—	—	—
SBP	1.03	(0.92, 1.06)	0.085	—	—	—
DBP	1.07	(0.94, 1.12)	0.613	—	—	—
Heart rate	0.88	(0.99, 1.22)	0.851	—	—	—
Serum creatinine	1.06	(1.02, 1.21)	0.005	0.87	(0.76, 1.13)	0.263
Total bilirubin	0.94	(1.00, 1.03)	0.123	—	—	—
Total cholesterol	0.89	(0.76, 1.04)	0.137	—	—	—
Triglyceride	0.81	(0.68, 0.96)	0.013	0.84	(0.76, 1.23)	0.071
HDL	0.78	(0.46, 1.34)	0.370	—	—	—
LDL	1.01	(0.85, 1.20)	0.901	—	—	—
LVEF	0.91	(0.84, 1.26)	0.342	—	—	—
Baseline serum uric acid	1.45	(1.03, 2.04)	0.032	1.42	(1.05, 1.87)	0.024

Abbreviations: BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; HDL = high-density lipoprotein; LDL = low-density lipoprotein; LVEF = left ventricular ejection fraction; PCI = percutaneous coronary intervention; CABG = cardiac artery bypass grafting; ACEI = angiotensin-converting enzyme inhibitor. Multivariate analyses: adjusted for serum creatinine, triglyceride, and history of heart failure.