Prognostic Factors and Nomograms to Predict Overall and Cancer-Specific Survival for Children with Wilms’ Tumor

Table 2

Univariate Cox’s regression analysis for OS and CSS in Wilms’ tumor patients from the training cohort.

Variables	Overall survival			Cancer-specific survival
	HR	95% CI		HR	95% CI
Sex
Male	Reference			Reference
Female	0.972	0.685-1.379	0.874	1.031	0.709-1.498	0.875
Age
≤3	Reference			Reference
3-18	1.917	1.351-2.721	<0.001	2.446	1.672-3.577	<0.001
Race
Other	Reference			Reference
White	0.837	0.406-1.723	0.629	0.737	0.356-1.524	0.411
Black	0.914	0.410-2.035	0.825	0.822	0.364-1.856	0.637
Laterality
Left	Reference			Reference
Right	0.778	0.534-1.134	0.191	0.740	0.493-1.110	0.145
Bilateral	2.370	1.366-4.111	0.002	2.486	1.403-4.405	0.002
Tumor size
≤4	Reference			Reference
4-7	2.703	1.014-7.204	0.047	3.333	0.965-11.512	0.057
>7	2.092	0.852-5.134	0.107	3.159	1.000-9.977	0.0499
Surgical status
No	Reference			Reference
Yes	0.258	0.131-0.509	<0.001	0.284	0.132-0.610	0.001
SEER historic stage A
Regional	Reference			Reference
Localized	0.704	0.433-1.145	0.158	0.482	0.279-0.832	0.009
Distant	2.716	1.770-4.167	<0.001	2.591	1.673-4.013	<0.001