Circular RNAs Hsa_circ_0002715 and Hsa_circ_0035197 in Peripheral Blood Are Novel Potential Biomarkers for New-Onset Rheumatoid Arthritis

Figure 3

ROC analysis of differentially expressed circRNAs in peripheral blood from new-onset RA patients. Diagnostic power of differentially expressed circRNAs in peripheral blood for RA vs. HC (a), RA vs. AS (b), RA vs. SLE (c, d), and RA vs. UA (e) was determined by ROC curve analysis. The results show the AUC for the sensitivity and specificity of each circRNA. The improved AUC for the combination of circRNAs are shown in (f, g). Area under the curve (AUC), ankylosing spondylitis (AS), circular RNAs (circRNAs), healthy controls (HC), receiver operating characteristic (ROC), and systemic lupus erythematosus (SLE).

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