Research Article
Prognostic Value of MicroRNAs in Patients after Myocardial Infarction: A Substudy of PRAGUE-18
Table 1
Baseline characteristics.
| | All patients | Survivors | Nonsurvivors | values |
| | | Median (5th-95th percentile) | | | Number of patients | 122 | 116 | 6 | | | Age (years) | 61.1 (40.4–76.8) | 61.1 (40.1–76.7) | 65.7 (56.1–81.0) | 0.166 | | Men (number, %) | 96 (78.7%) | 91 (78.4%) | 5 (83.3%) | 0.999 | | BMI | 27.6 (22.2–34.3) | 27.6 (22.1–34.3) | 26.7 (24.7–44.1) | 0.929 | | Drug used: prasugrel (number, %) | 65 (53.3%) | 62 (53.4%) | 3 (50.0%) | 0.999 | | Drug used: ticagrelor (number, %) | 57 (46.7%) | 54 (46.6%) | 3 (50.0%) | | STEMI (number, %) | 121 (99.2%) | 115 (99.1%) | 6 (100.0%) | 0.999 | | Left bundle branch block (LBBB) (number, %) | 1 (0.8%) | 1 (0.9%) | 0 (0.0%) | 0.999 | | Right bundle branch block (RBBB) (number, %) | 1 (0.8%) | 1 (0.9%) | 0 (0.0%) | 0.999 | | Hyperlipidaemia (number, %) | 36 (29.5%) | 35 (30.2%) | 1 (16.7%) | 0.669 | | Obesity (number, %) | 23 (18.9%) | 22 (19.0%) | 1 (16.7%) | 0.999 | | Arterial hypertension (number, %) | 56 (45.9%) | 52 (44.8%) | 4 (66.7%) | 0.412 | | Smoking (number, %) | 84 (68.9%) | 80 (69.0%) | 4 (66.7%) | 0.999 | | Diabetes mellitus (number, %) | 17 (13.9%) | 16 (13.8%) | 1 (16.7%) | 0.999 | | Time since the first symptoms to admission (hours) | 3.0 (0.5–36.0) | 3.0 (0.5–12.0) | 6.0 (3.0–72.0) | 0.061 | | Left ventricular ejection fraction (%) | 50.0 (30.0–60.0) | 55.0 (30.0–60.0) | 45.0 (30.0–50.0) | 0.054 | | Laboratory values (median (5th-95th percentile)) | | | | | | hsTnT (at admission) (ng/L) | 86.0 (12.0–1325.0) | 84.0 (12.0–1325.0) | 201.5 (27.0–4978.0) | 0.257 | | hsTnT (24 hours after admission) (ng/L) | 2432.0 (377.0–9651.0) | 2324.0 (368.0–9651.0) | 4306.5 (1526.0–15114.0) | 0.201 | | Myoglobin (at admission) (μg/L) | 198.0 (30.0–1385.0) | 176.0 (30.0–1547.0) | 652.0 (161.0–1317.0) | 0.066 | | Creatine kinase (at admission) (μkat/L) | 3.9 (1.4–23.7) | 3.8 (1.3–23.7) | 6.4 (2.6–26.8) | 0.097 | | NT-proBNP (at admission) (ng/L) | 757.0 (105.0–4142.0) | 666.5 (104.0–4285.0) | 1373.5 (904.0–3096.0) | 0.074 | | Cystatin C (at admission) (mg/L) | 121; 0.99 (0.80–1.47) | 1.00 (0.79–1.49) | 0.92 (0.85–1.09) | 0.417 | | GDF-15 (at admission) (ng/L) | 807.1 (372.8–1827.7) | 796.3 (372.8–1827.7) | 1044.9 (357.3–1848.8) | 0.305 |
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GDF-15 = growth/differentiation factor 15; hsTnT = high-sensitivity troponin T; NT-proBNP = N-terminal prohormone of brain natriuretic peptide; STEMI = acute myocardial infarction with ST-segment elevation.
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