Systematic Meta-analysis Revealed an Association of PGC-1α rs8192678 Polymorphism in Type 2 Diabetes Mellitus

Table 1

Characteristics of the included studies about the association between PGC-1αrs8192678 polymorphism and T2DM.

Author	Year	Ethnicity	T2DM				Control				Matching variables	Chi-square values of HWE	value
			GG	GA	AA	Total	GG	GA	AA	Total
Chen et al. [26]	2004	Chinese	155	255	84	494	185	264	106	555	Age, gender	0.466	0.495
De-yao et al. [27]	2014	Chinese	165	175	90	430	190	181	60	431	Age, gender	2.492	0.115
Hui et al. [28]	2009	Chinese	71	28	41	140	47	30	11	88	Gender, BMI	1.276	0.259
Kim et al. [14]	2005	Korean	251	355	152	762	88	163	51	303	Gender	2.779	0.096
Lu et al. [29]	2006	Chinese	44	55	21	120	54	41	11	106	—	0.581	0.446
Sun et al. [30]	2006	Chinese	122	190	78	390	181	256	88	525	Age, gender, BMI	0.025	0.876
Weng et al. [13]	2010	Chinese	91	129	56	276	340	502	207	1049	Age, gender, BMI	0.78	0.377
Zhang et al. [31]	2007	Chinese	97	121	45	263	144	111	27	282	Age, BMI	0.679	0.41
Zhu et al. [8]	2017	Chinese	138	251	108	502	250	382	150	784	Age, gender	0.036	0.85
Zhu et al. [32]	2009	Chinese	181	303	111	595	143	240	112	495	Gender, BMI	0.347	0.556
Ek et al. (a) [19]	2001	Caucasian	186	200	68	454	97	80	21	198	—	0.541	0.462
Ek et al. (b) [19]	2001	Caucasian	76	97	28	201	146	116	31	293	—	1.2	0.273
Fanelli et al. [33]	2005	Caucasian	51	56	18	125	86	96	41	223	Gender	2.431	0.126
Jemaa et al. [34]	2015	Caucasian	166	231	90	478	176	170	56	402	Age, gender	2.055	0.152
Kruzliak et al. [12]	2015	Caucasian	80	334	467	881	40	147	161	348	Age, gender	0.529	0.467
Kunej et al. [35]	2004	Caucasian	141	129	35	305	114	111	15	240	Age, gender, BMI	3.156	0.076
Lacquemant et al. [15]	2002	Caucasian	129	137	44	310	163	159	47	369	—	0.705	0.401
Shokouhi et al. [9]	2015	Caucasian	127	43	3	173	159	13	1	173	Age	1.531	0.216
Bhat et al. (a) [11]	2007	Indian	68	103	28	199	112	80	21	213	BMI	1.401	0.237
Bhat et al. (b) [11]	2007	Indian	69	70	13	152	143	96	19	258	BMI	0.269	0.604
Sharma et al. [25]	2018	Indian	220	254	80	554	258	249	64	571	Age, sex	0.112	0.737
Cheema et al. (a) [36]	2015	African	92	4	14	110	102	14	0	116	Gender, BMI	0.478	0.489
Cheema et al. (b) [36]	2015	African	103	19	2	124	104	18	0	122	Gender	0.774	0.379

HWE: Hardy-Weinberg equilibrium; value: value of HWE.