Plasma Betatrophin Levels and Carotid Atherosclerosis
Table 1
Clinical characteristics of subjects with and without plaque.
Plaque (-) ()
value
Plaque (+) ()
Plaque ()
Plaque ()
Age (years)
<0.001
Gender (male)
42 (47%)
<0.025
42 (67%)
20 (65%)
22 (69%)
Body mass index (kg/m2)
NS
Hypertension
43 (48%)
NS
35 (56%)
15 (48%)
20 (63%)
Systolic BP (mmHg)
NS
DM
4 (4%)
NS
6 (10%)
3 (10%)
3 (9%)
HbA1c (%)
NS
Smoking
10 (11%)
NS
5 (8%)
3 (10%)
2 (6%)
Hypercholesterolemia
38 (42%)
NS
26 (41%)
13 (42%)
13 (42%)
Statin
17 (19%)
NS
11 (17%)
6 (19%)
5 (16%)
LDL cholesterol (mg/dL)
NS
HDL cholesterol (mg/dL)
NS
Hypertriglyceridemia
19 (21%)
NS
14 (9%)
6 (19%)
3 (9%)
TG (mg/dL)
NS
hsCRP levels (mg/L)
0.34 [0.19, 0.68]
NS
0.38 [0.19, 0.83]
0.35 [0.14, 0.68]
0.38 [0.19, 0.90]
Betatrophin levels (pg/mL)
729 [569, 1046]
<0.025
906 [728, 1116]
802 [672, 976]
978 [819, 1139]
Betatrophin >800 pg/mL
40 (44%)
<0.025
41 (65%)
16 (52%)
25 (78%)
Carotid ultrasonography
Mean IMT (mm)
<0.001
Plaque score
<0.001
Data represent the or the number (%) of subjects, except for hsCRP and betatrophin levels presented as the median value and interquartile range. SBP = systolic blood pressure; TG = triglyceride.
