Overexpression of eIF3D in Lung Adenocarcinoma Is a New Independent Prognostic Marker of Poor Survival

Table 2

Univariate analysis of OS in LUAD patients.

Parameters	Univariate analysis
	HR	95% CI (lower-upper)	value
Age
<65 ()	1.000
≥65 ()	1.145	0.849-1.545	0.375
Gender
Female ()	1.000
Male ()	1.030	0.768-1.382	0.843
Pathological stage
I/II ()	1.000
III/IV ()	2.581	1.884-3.535	<0.001
Radiation therapy
No ()	1.000
Yes ()	2.016	1.372-2.962	<0.001
Residual tumour
R0 ()	1.000
R1/R2 ()	4.187	2.333-7.512	<0.001
Smoking history
1 ()	1.000
2/3/4/5 ()	0.888	0.588-1.341	0.571
Mutations
No ()	1.000
Yes ()	0.866	0.558-1.346	0.523
Targeted therapy
No ()	1.000
Yes ()	1.159	0.830-1.620	0.386
EIF3B expression
Low ()	1.000
High ()	1.563	1.156-2.111	0.004
eIF3D expression
Low ()	1.000
High ()	1.377	1.024-1.854	0.034
EIF3L expression
Low ()	1.000
High ()	0.710	0.528-0.955	0.023
EIF3M expression
Low ()	1.000
High ()	1.521	1.127-2.053	0.006

Indicates statistical significance ().