Differed IL-1 Beta Response between Active TB and LTBI Cases by Ex Vivo Stimulation of Human Monocyte-Derived Macrophage with TB-Specific Antigen

<div>Inflammasomal gene expression in human monocyte-derived macrophages from 12 active tuberculosis (TB) patients, 12 latent TB infection (LTBI) cases, and 23 uninfected contacts after 6 hr antigen stimulation measured by real-time PCR. ESAT-6: early secretory antigenic target-6KD; IL-1b: interleukin-1 beta; LPS: lipopolysaccharide; MR: mannose receptor; NLRP3: NLR Family Pyrin Domain Containing 3; PPD: tuberculin purified protein derivative; TNFa: tumor necrosis factor-alpha.</div>

Disease Markers

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Figure 1

Figure 1: Differed IL-1 Beta Response between Active TB and LTBI Cases by Ex Vivo Stimulation of Human Monocyte-Derived Macrophage with TB-Specific Antigen 

Figure 1 | Differed IL-1 Beta Response between Active TB and LTBI Cases by Ex Vivo Stimulation of Human Monocyte-Derived Macrophage with TB-Specific Antigen 