Research Article
Differed IL-1 Beta Response between Active TB and LTBI Cases by Ex Vivo Stimulation of Human Monocyte-Derived Macrophage with TB-Specific Antigen
Figure 2
Inflammasomal gene expression in human monocyte-derived macrophages from 4 latent TB infection (LTBI) cases and 6 uninfected contacts after 6 hr and 24 hr antigen stimulations measured by real-time PCR. ESAT-6, early secretory antigenic target-6KD; IL-1b: interleukin-1 beta; LPS: lipopolysaccharide; MR: mannose receptor; NLRP3: NLR Family Pyrin Domain Containing 3; PPD: tuberculin purified protein derivative; TNFa: tumor necrosis factor-alpha.