Role of Plasma Calreticulin in the Prediction of Severity in Septic Patients
Table 1
Baseline patient characteristics.
Characteristics
Control group ()
All patients ()
Survivors ()
Nonsurvivors ()
value
Age (years)
63 (60-66)
66 (54-76)
64 (52-75)
70 (60-80)
0.050
Sex (male/female)
18/22
93/34
63/24
30/10
0.761
APACHE II score
—
19 (15-25)
17 (13-22)
25 (17-29)
0.001
ICU stay (day)
—
19 (8-28)
25 (15-28)
8 (5-13)
0.001
Temperature
—
38.2 (37.7-38.7)
38.2 (37.8-38.2)
38.7 (37.1-38.7)
0.634
Heart rate
—
103 (94-117)
102 (90-115)
110 (99-120)
0.045
Respiration rate
—
23 (20-27)
22 (20-26)
25 (17.5-28.75)
0.002
MAP (mmHg)
—
80 (72.3-91.7)
82 (76-95)
75 (67-85)
0.007
WBC, 109/L
—
12.8 (9.7-17.8)
12 (9.21-15.3)
16.6 (11.7-23.2)
0.001
PMN, 109/L
—
11.2 (8.5-15.5)
10.2 (7.9-13.4)
14.7 (10.7-22)
0.001
PaO2/FiO2
—
177 (123-225)
194 (153-242)
110.5 (83-201.5)
0.001
Lactate (mmol/l)
—
1.7 (1.4-2.3)
1.61 (1.4-2.1)
2.1 (1.6-3.8)
0.003
PCT (ng/ml)
—
1.43 (0.33-10.91)
0.97 (0.29-8.55)
3.8 (0.85-12.6)
0.045
Calreticulin (pg/ml)
240 (113-283)
418 (177-196)
333 (107-129)
899 (354-450)
0.003
Data are expressed as medians (interquartile range). APACHE II score: Acute Physiology and Chronic Health Evaluation score II; ICU: intensive care unit; MAP: mean arterial pressure; WBC: white blood cell; PMN: neutrophils; PCT: procalcitonin.
