Research Article
Preoperative Plasma Fibrinogen and Serum Albumin Score Is an Independent Prognostic Factor for Resectable Stage II-III Gastric Cancer
Table 2
Univariate analysis of the factors associated with the prognosis of gastric cancer.
| | Variable | Classification | | Death (%) | 5-year survival rate | HR (95% CI) | |
| | Age (years) | ≤60 | 434 | 177 (40.8) | 59.6 | 1.00 | | | >60 | 408 | 203 (49.8) | 51.0 | 1.32 (1.08-1.61) | 0.008 |
| | Gender | Male | 629 | 288 (45.8) | 55.0 | 1.00 | | | Female | 213 | 92 (43.2) | 56.8 | 0.94 (0.74-1.18) | 0.577 |
| | TNM stage | I | 134 | 13 (9.7) | 92.3 | 1.00 | | | II | 318 | 109 (34.3) | 68.1 | 4.33 (2.44-7.69) | <0.001 | | III | 390 | 258 (66.2) | 30.9 | 12.66 (7.24-22.14) | <0.001 |
| | Histological grading | Poorly differentiated | 586 | 274 (46.8) | 53.3 | 1.00 | | | Well or moderately differentiated | 256 | 106 (41.4) | 60.4 | 0.79 (0.63-0.99) | 0.040 |
| | Vascular invasion | Negative | 225 | 45 (20.0) | 81.9 | 1.00 | | | Positive | 617 | 335 (54.3) | 45.5 | 3.69 (2.69-5.04) | <0.001 |
| | Neural invasion | Negative | 377 | 115 (30.5) | 71.2 | 1.00 | | | Positive | 465 | 265 (57.0) | 42.2 | 2.49 (2.01-3.11) | <0.001 |
| | Pathological type | Tubular adenocarcinoma | 719 | 325 (45.2) | 55.9 | 1.00 | | | Signet-ring cell carcinoma | 75 | 31 (41.3) | 56.7 | 0.92 (0.64-1.33) | 0.646 | | Other types | 48 | 24 (50.0) | 47.8 | 1.19 (0.79-1.81) | 0.411 |
| | Chemotherapy | Yes | 258 | 111 (43.0) | 57.9 | 1.00 | | | No | 584 | 269 (46.1) | 54.4 | 1.16 (0.93-1.45) | 0.192 |
| | Fibrinogen | ≤3.39 | 521 | 215 (41.3) | 59.4 | 1.00 | | | >3.39 | 321 | 165 (51.4) | 49.0 | 1.41 (1.15-1.73) | 0.001 |
| | Albumin | >34.9 | 558 | 232 (41.6) | 58.5 | 1.00 | | | ≤34.9 | 284 | 148 (52.1) | 49.5 | 1.40 (1.14-1.13) | 0.001 |
| | Fib-Alb score | 0 | 376 | 144 (38.3) | 62.4 | 1.00 | | | 1 | 327 | 159 (48.6) | 51.0 | 1.42 (1.14-1.79) | 0.002 | | 2 | 139 | 77 (55.4) | 47.1 | 1.76 (1.34-2.32) | <0.001 |
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