Identification of Serum CMTM2 as a Potential Biomarker for HBV-Related Disorders

Figure 6

HBx induced ubiquitination-mediated CMTM2 degradation. HBx enhanced CMTM2 ubiquitination in HepG2 cell (a). K48-linked CMTM2 ubiquitination and K63-linked CMTM2 ubiquitination were immunoprecipitated with CMTM2 antibodies and detected by immunoblotting (b, c).

(a)

(b)

(c)