Assessment of Serum Tumor Markers for Predicting Ocular Metastasis in Lung Adenocarcinoma: A Retrospective Study

Table 5

The cutoff value, sensitivity, specificity, and AUC for single risk factor in predicting OM in lung adenocarcinoma patients.

Factor	Cutoff value	Sensitivity (%)	Specificity (%)	AUC
CYFRA21-1 (ng/mL)	6.785	0.936	0.794	0.928	<0.001
CA-125 (U/mL)	66.295	0.745	0.744	0.749	<0.001
CA-153 (U/mL)	13.005	0.830	0.580	0.758	<0.001
CYFRA21-1+CA-125	—	0.814	0.851	0.890	<0.001
CYFRA21-1+CA-153	—	0.769	0.872	0.880	<0.001
CA-125+CA-153	—	0.682	0.809	0.809	<0.001
CYFRA21-1+CA-125+CA-153	—	0.807	0.851	0.888	<0.001

Sensitivity and specificity were obtained at the point of cutoff value. represented statistical significance. AUC: area under the curve; CI: confidence interval; OM: ocular metastasis.