MicroRNA-7 as a Potential Biomarker for Prognosis in Pancreatic Cancer

Figure 4

miR-7 inhibits autophagy and aerobic glycolysis in pancreatic cancer. (a) RNA-seq data from TCGA pancreatic ductal adenocarcinoma project was applied to analyze the expression of glycolysis genes. (b) Representative images of immunohistochemistry staining for LC3 and LDHA and in situ hybridization for miR-7 in pancreatic tissue microarray were shown. Scale bar: 100 μm (main); 250 μm (inset). (c) Relationship between miR-7 and LC3 expression (A) and miR-7 and LDHA (B) in pancreatic tissue microarray.

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