Research Article

Circulating Sestrin Levels Are Increased in Hypertension Patients

Table 1

Clinical characteristics in each group.

CharacteristicsControlHypertension
TotalGrade IGrade IIGrade III

Age (years)
Male (, %)66 (66.0)287 (71.8)102 (72.9)126 (70.0)59 (73.4)
Smoking (, %)33 (33.0)145 (36.3)47 (33.6)62 (34.4)36 (45.0)
History (years)
SBP (mmHg)
DBP (mmHg)
HR (HR)
BMI (kg/m2)
TC (mmol/L)
TG (mmol/L)
HDL-C (mmol/L)
LDL-C (mmol/L)
Glu (mmol/L)
HbAlc (%)
CRRA (μmol/L)
CRP (mg/L)
Hcy (pg/mL)
Ang II (pg/mL)
CAP200 (50.0)52 (37.1)#93 (51.7)$55 (68.8)#,$,&
Medical treatments (, %)
ACEI/ARB244 (61.0)70 (50.0)#111 (61.1)63 (78.8)#
β-Blocker179 (44.8)52 (37.1)83 (46.1)44 (55.0)
CCB338 (84.5)109 (77.9)#159 (88.3)70 (87.5)
Diuretics244 (41.3)30 (21.4)#74 (41.1)$61 (76.3)#,$,&

History: the duration of hypertension; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; BMI: body mass index; TC: total cholesterol; TG: total triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Glu: fasting glucose; HbA1c: hemoglobin a1c; CRP: C-reactive protein; CREA: creatinine; Hcy: homocysteine; Ang II: angiotensin II; CAP: carotid atherosclerotic plaque; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; CCB: calcium channel blocker. vs. the control group, # vs. the total group, $ vs. the grade I group, and & vs. the grade II group.