FASN Protein Overexpression Indicates Poor Biochemical Recurrence-Free Survival in Prostate Cancer

Table 2

FASN expression status in TMA.

Variable	No. of successfully analysed samples	FASN immunohistochemistry result
		Low	High
Tissue type	188			<0.001
Prostate cancer	188	57	131
Paracancerous tissue	188	118	70
Preoperative PSA level (ng/ml)	187			0.618
<4	2	0	2
4-10	37	9	28
10-20	69	23	46
≥20	79	24	55
Gleason score	182			0.004
	9	7	2
	60	21	39
	34	12	22
	79	17	62
pT category	188			0.569
pT2a–2b	34	12	22
pT2c	79	25	54
pT3a-b	71	18	53
pT4	4	2	2
pN category	153			0.294
pN0	121	38	83
pN+	32	7	25
Seminal vesicle invasion	188			0.011
Yes	42	6	36
No	146	51	95
Surgical margin	188			0.187
Negative	106	28	78
Positive	82	29	53