Association of Soluble Klotho Level with Adverse Outcomes in Patients on Maintenance Hemodialysis

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Outcomes</td><td class="align_center"><svg height="12.7112pt" id="M59" style="vertical-align:-3.403299pt" version="1.1" viewbox="-0.0498162 -9.3079 111.515 12.7112" width="111.515pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M667 0V28C619 34 599 43 546 100C496 154 386 277 311 372C378 440 449 512 488 547C551 605 575 615 650 622V650H410V622L433 619C478 614 479 604 449 568C404 513 337 443 282 390C254 364 234 350 212 345V520C212 609 222 616 299 622V650H41V622C120 616 128 611 128 520V128C128 41 120 34 44 28V0H304V28C221 34 212 41 212 128V318C229 321 242 318 266 291C355 185 436 87 514 0H667Z"></path></g><g transform="matrix(.013,0,0,-0.013,8.853,0)"><path d="M238 0V26C174 32 166 38 166 104V712C132 700 70 683 18 677V653C81 647 87 645 87 577V104C87 38 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colspan="4"><hr/></td></tr><tr><td class="align_left">All-cause mortality</td><td class="align_center">29 (28.4%)</td><td class="align_center">11 (11.6%)</td><td class="align_center">0.003</td></tr><tr><td class="align_left">Cardiovascular</td><td class="align_center">11 (11.0%)</td><td class="align_center">5 (5.2%)</td><td class="align_center">/</td></tr><tr><td class="align_left">Infection</td><td class="align_center">6 (6.0%)</td><td class="align_center">3 (3.1%)</td><td class="align_center">/</td></tr><tr><td class="align_left">Tumor</td><td class="align_center">3 (3.0%)</td><td class="align_center">1 (1.0%)</td><td class="align_center">/</td></tr><tr><td class="align_left">Others</td><td class="align_center">9 (9.0%)</td><td class="align_center">2 (2.1%)</td><td class="align_center">/</td></tr><tr><td class="align_left">Cardiovascular morbidity</td><td class="align_center">34/89 (38.2%)</td><td class="align_center">17/87 (19.5%)</td><td class="align_center">0.006</td></tr><tr><td class="align_left">Composite endpoints</td><td class="align_center">52 (51.0%)</td><td class="align_center">23 (24.2)</td><td class="align_center">&lt;0.001</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Clinical outcomes according to median Klotho level.</div>

Disease Markers

tab2

Table 2

Table 2: Association of Soluble Klotho Level with Adverse Outcomes in Patients on Maintenance Hemodialysis 