Association of Soluble Klotho Level with Adverse Outcomes in Patients on Maintenance Hemodialysis

Table 3

Univariate Cox regression analysis for combined adverse events.

Parameters	HR (95% CI)	value
Univariate analysis
Age	1.047 (1.026-1.068)	<0.001
Gender (male/female)	1.463 (0.935-2.289)	0.096
Hypertension (yes/no)	1.155 (0.624-2.137)	0.647
Diabetes (yes/no)	0.583 (0.363-0.935)	0.025
Vitamin D (yes/no)	1.524 (0.892-2.605)	0.123
ACEI/ARB (yes/no)	1.274 (0.743-2.183)	0.378
Dialysis vintage (year)	0.930 (0.872-0.992)	0.027
KT/V (per week)	0.903 (0.624-1.307)	0.588
(mg^2/dL^2)	0.854 (0.722-1.010)	0.066
HGB (g/L)	0.995 (0.981-1.010)	0.495
ALB (g/L)	0.903 (0.846-0.965)	0.002
Klotho (median)	2.248 (1.393-3.625)	0.001
FGF23 (median)	0.595 (0.377-0.943)	0.027
iPTH (ng/mL)	0.999 (0.999-1.000)	0.080