Association of WISP1/CCN4 with Risk of Overweight and Gestational Diabetes Mellitus in Chinese Pregnant Women

Table 3

Univariate and multivariate regression analyses of WISP1.

Variables	Univariate		Multivariate
		value	(95% CI)	value
Age (years)	0.080	0.160	—	—
Gestational age (weeks)	0.109	0.055	—	—
Height (cm)	0.050	0.378	—	—
Weight (kg)	0.136	0.016	0.003 (-0.018, 0.025)	0.752
BMI (kg/m^2)	0.124	0.028	-0.018 (-0.077, 0.041)	0.550
FBG (mmol/L)	0.168	0.003	0.318 (0.133, 0.603)	0.001
OGTT 1 h (mmol/L)	0.091	0.108	—	—
OGTT 2 h (mmol/L)	0.044	0.439	—	—
SBP (mmHg)	0.169	0.003	0.007 (0.000, 0.013)	0.044
DBP (mmHg)	0.085	0.132	—	—
Hemoglobin (g/L)	-0.080	0.158	—	—
Inflammatory marker
WBC count (×10^9/L)	-0.063	0.263	—	—
IL-6 (pg/mL)	-0.041	0.471	—	—
CRP (mg/L)	0.135	0.017	0.025 (-0.002, 0.052)	0.065
Liver function marker
Total protein (g/L)	0.461	<0.001	0.025 (-0.002, 0.053)	0.074
Albumin (g/L)	0.417	<0.001	0.005 (-0.026, 0.037)	0.750
Albumin/globulin	0.013	0.816	—	—
ALT (U/L)	0.087	0.123	—	—
AST (U/L)	0.247	<0.001	0.016 (0.002, 0.030)	0.028
Prealbumin (g/L)	0.325	<0.001	-0.848 (-2.605, 0.909)	0.343
Total bilirubin (μmol/L)	0.198	0.055	—	—
CB (μmol/L)	0.176	0.002	-0.172 (-0.354, 0.011)	0.065
UCB (μmol/L)	0.189	0.001	0.103 (0.001, 0.205)	0.048
Total bile acid (μmol/L)	0.227	<0.001	0.032 (-0.036, 0.101)	0.927
MAO (U/L)	0.290	<0.001	-0.019 (-0.063, 0.025)	0.404
Renal function marker
Urea (mmol/L)	0.226	<0.001	0.043 (-0.104, 0.190)	0.564
Creatinine (μmol/L)	0.108	0.057	—	—
Uric acid (μmol/L)	0.365	<0.001	0.001 (-0.001, 0.003)	0.322
Cystatin C (mg/L)	0.498	<0.001	1.426 (0.659, 2.193)	<0.001
Complement C1q (mg/L)	0.272	<0.001	-0.006 (-0.009, -0.002)	0.001
Lipids
Triglyceride (mmol/L)	0.251	<0.001	-0.138 (-0.287, 0.010)	0.068
Cholesterol (mmol/L)	0.288	<0.001	0.037 (-0.007, 0.080)	0.102
HDL-C (mmol/L)	0.157	0.005	-0.582 (-1.097, -0.067)	0.027
LDL-C (mmol/L)	0.242	<0.001	-0.267 (-0.659, 0.125)	0.182
Apolipoprotein A1 (g/L)	0.362	<0.001	0.299 (-0.361, 0.959)	0.373
Apolipoprotein B (g/L)	0.361	<0.001	1.180 (-0.188, 2.548)	0.091