Research Article
Serum TNF-α Level Is Associated with Disease Severity in Adult Patients with Immunoglobulin A Vasculitis Nephritis
Table 3
Comparison of IgAV-N and IgAN.
| | IgAV-N | IgAN | value |
| | Age (years) | 29 (25-37) | 29 (27-34) | 0.228 | | Female, no. (%) | 36 (67.9%) | 35 (66.0%) | 0.836 | | Diabetes, no. (%) | 1(1.9%) | 1(1.9%) | 1.000 | | MBP (mmHg) | 87 (83-96) | 87 (78-93) | 0.235 | | TNF-α (pg/mL) | 7.4 (5.7-9.4) | 8.0 (6.7-9.9) | 0.116 | | sCr (μmol/L) | 75 (65-94) | 79 (69-93) | 0.359 | | eGFR (mL/min/1.73 m2) | 101.1 (76.9-119.2) | 102.8 (80.8-121.9) | 0.716 | | Cys-C (mg/dL) | 0.90 (0.77-1.26) | 0.93 (0.77-1.11) | 0.987 | | Urinary red blood cell (/μL) | 53 (30-161) | 39 (9-108) | 0.080 | | uPCR (mg/g Cr) | 540 (236-1001) | 524 (183-986) | 0.897 | | PER (g/24 h) | 0.66 (0.35-1.38) | 0.76 (0.44-1.30) | 0.663 | | Albumin (g/L) | 43 (39-46) | 43 (42-45) | 0.512 | | IgA (g/L) | 2.79 (2.07-3.53) | 2.38 (1.92-3.22) | 0.165 | | Glucocorticoid, no. (%) | 21 (39.6%) | 28 (52.8%) | 0.173 | | Immunosuppressants, no. (%) | 18 (34.0%) | 28 (52.8%) | 0.050 |
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IgAV-N: immunoglobulin A vasculitis nephritis; IgAN: immunoglobulin A nephropathy; MBP: mean blood pressure; sCr: serum creatinine; eGFR: estimated glomerular filtration rate; Cys-C: serum cystatin C; uPCR: urinary protein to serum creatinine ratio; PER: urine protein excretion.
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