Research Article

ZNF143 Suppresses Cell Apoptosis and Promotes Proliferation in Gastric Cancer via ROS/p53 Axis

Figure 2

ZNF143 promoted the proliferation of GC cells in vitro. (a, b) Effects of ZNF143 on the proliferation ability of GC cells explored using the CCK-8 assay. (c) ZNF143 knockdown inhibited the proliferation of HGC27 cells, and overexpression of ZNF143 promoted the proliferation of BGC823 cells, as detected using EDU assays. (d) Rate of EDU-positive cells. (e) Colony formation assays showing that ZNF143 knockdown inhibited the proliferation of HGC27 cells, while the overexpression of ZNF143 promoted the proliferation of BGC823 cells. (f) Number of clones formed. , , and . The data were expressed as . CCK8: Cell Counting Kit-8; EDU: 5-ethynyl-2-deoxyuridine.
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