ZNF143 Suppresses Cell Apoptosis and Promotes Proliferation in Gastric Cancer via ROS/p53 Axis

Figure 4

Overexpression of ZNF143 inhibited p53-dependent ROS-mediated apoptosis in BGC823. (a) Protein level of ZNF143 detected using Western blot assay. (b) Apoptotic rate of GC cells measured using flow cytometry. (c, d) ROS level of GC cells detected using confocal microscopy. (e) Expression of ZNF143 and p53 in GC cells analyzed using Western blot assay. (f) Apoptotic rate of GC cells measured using flow cytometry. (g, h) ROS level of GC cells after different treatments were detected using confocal microscopy. , , and . The data were expressed as . NAC: N-acetylcysteine; ROS, reactive oxygen species.

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