Interleukin-18 Is a Prognostic Marker and Plays a Tumor Suppressive Role in Colon Cancer

Table 1

Correlation between IL-18 expression and clinicopathological features in patients with colon cancer ().

Variable		IL-18 expression			value
		Negative (76)	Weak (23)	Strong (17)
Age					0.668
<60	54	36	9	9
≥60	62	40	14	8
Gender					0.826
Male	68	46	13	9
Female	48	30	10	8
Location					0.603
Right	58	38	13	7
Transverse	29	17	7	5
Left	29	21	3	5
T stage					0.001
T1+T2	63	33	20	10
T3+T4	53	43	3	7
N stage					0.191
N0	64	46	9	9
N1+N2	52	30	14	8
M stage					0.585
M0	114	74	23	17
M1	2	2	0	0
AJCC stage					0.013
I	45	22	11	12
II	22	12	7	3
III	37	31	4	2
IV	13	11	1	1
Differentiation					0.407
Well	39	26	7	6
Moderate	58	35	15	8
Poor	19	15	1	3

P values are based on chi-squared or Fisher’s exact test. indicates a significant association among the variables.