Elevated Levels of Serum Neurofilament Light Chain Associated with Cognitive Impairment in Vascular Dementia

Table 3

Association between MoCA scores and various parameters in VaD.

	Regression coefficient		95% CI
Age (years)	0.138	0.184	0.725-1.203
Gender	0.263	0.196	0.788-1.194
Education (years)	0.214	0.086	0.672 - 1.145
SBP (mmHg)	0.386	0.437	0.783 - 1.092
DBP (mmHg)	0.379	0.322	0.561 - 1.236
TG (mmol/L)	0.272	0.195	0.826 - 1.215
TC (mmol/L)	0.305	0.618	0.487 - 1.309
HDL-C (mmol/L)	0.403	0.239	0.799 - 1.167
LDL-C (mmol/L)	0.260	0.193	0.915 - 1.128
FBG (mmol/L)	0.621	0.264	0.871 - 1.053
Serum NfL (pg/mL)	0.317	0.021	1.634 - 2.481

MoCA: Montreal cognitive assessment scale; VaD: vascular dementia; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; FBG: fasting plasma glucose; NfL: neurofilament light chain.