| Variables | Number of studies | del vs. ins | | del/del vs. ins/ins | | del/del+del/ins vs. ins/ins | | del/del vs. ins/ins+del/ins | | del/ins vs. ins/ins | | OR (95% CI) | | OR (95% CI) | | OR (95% CI) | | OR (95% CI) | | OR (95% CI) | |
| Overall | 12 | 0.95 (0.80, 1.13)r | 0.54 | 1.09 (0.75, 1.57)r | 0.67 | 0.97 (0.79, 1.19)b | 0.78 | 1.02 (0.76, 1.38)r | 0.88 | 0.94 (0.80,1.100)r | 0.43 | Cancer type | | | | | | | | | | | | Gastric cancer | 3 | 0.79 (0.72, 0.86)r | 0.00 | 0.90 (0.35, 2.31)r | 0.82 | 0.88 (0.53, 1.44)r | 0.60 | 0.74 (0.59, 0.91)a | 0.005 | 0.84 (0.77, 0.98)r | 0.03 | Colorectal cancer | 3 | 0.96 (0.65, 1.40)r | 0.82 | 0.96 (0.43, 2.16)r | 0.93 | 0.94 (0.60, 1.45)r | 0.77 | 0.99 (0.52, 1.87)r | 0.98 | 0.93 (0.65, 1.34)r | 0.71 | Others | 6 | 1.06 (0.82, 1.36)r | 0.68 | 1.24 (0.72, 2.14)r | 0.93 | 1.03 (0.76, 1.40)r | 0.84 | 1.25 (0.81, 1.91)r | 0.31 | 1.07 (0.97, 1.17)r | 0.16 | Ethnicity | | | | | | | | | | | | Chinese | 11 | 0.98 (0.82, 1.17)r | 0.79 | 1.15 (0.79, 1.68)r | 0.47 | 1.01 (0.82, 1.24)r | 0.94 | 1.06 (0.79, 1.44)r | 0.69 | 0.96 (0.82, 1.13)r | 0.63 | Iran | 1 | 0.61 (0.42, 0.89)r | — | 0.43 (0.17, 1.11)r | — | 0.58 (0.37, 3.91)r | — | 0.51 (0.20, 1.30)r | — | 0.61 (0.38, 0.99)r | — | Source of controls | | | | | | | | | | | | PB | 10 | 0.92 (0.76, 1.11)r | 0.38 | 1.05 (0.70, 1.57)r | 0.80 | 0.95 (0.76, 1.17)r | 0.62 | 0.99 (0.71, 1.36)r | 0.93 | 0.91 (0.78, 1.08)r | 0.28 | HB | 2 | 1.10 (0.57, 2.15)r | 0.77 | 1.30 (0.34, 4.97)r | 0.71 | 1.12 (0.49, 2.53)r | 0.79 | 1.23 (0.45, 3.36)r | 0.68 | 1.09 (0.54, 2.20)r | 0.82 | Cancer stage | | | | | | | | | | | | Stage I+II | 7 | 1.05 (0.86, 1.28)r | 0.62 | 1.16 (0.80, 1.66)r | 0.44 | 1.06 (0.81,1.37)r | 0.68 | 1.18 (0.89, 1.56)r | 0.24 | 1.01 (0.75 1.36)vr | 0.94 | Stage III+IV | 7 | 0.75 (0.50, 1.11)r | 0.15 | 0.76 (0.35, 1.61)r | 0.47 | 0.70 (0.44, 1.13)r | 0.14 | 0.94 (0.54, 1.63)r | 0.82 | 0.68 (0.43,1.08)r | 0.10 |
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