Identification of PDL1-Related Biomarkers to Select Lung Adenocarcinoma Patients for PD1/PDL1 Inhibitors

Table 2

Top 10 transcription factor predictions of candidate genes.

BRCA1		BRIP1		EREG
TF	Motif	TF	Motif	TF	Motif
RFX4	GGTTTCCGTGGCAACG	NFYB	AGCTCGACCAATCAC	E2F6	GGGCGGGAGCA
RFX5	CGTTGCCACGGAAACC	TFDP1	GGGCGGGAGGC	RXRG	GAGTGCACGGGCAGGGCG
RFX5	GGTTTCCGTGGCAACG	CTCFL	GTCGAGGGGGCGGG	RARA	AGTGCACGGGCAGGGCG
RFX4	CGTTGCCACGGAAACC	HAND1	GGACTGGGGC	E2F6	GGGAGGGAGGA
RFX2	CGTTGCCACGGAAACC	SP2	TTCCCGCCTCCCGCC	NR2F1	GTGAGGTCAAGAG
RFX2	GGTTTCCGTGGCAACG	CTCFL	GGACTGGGGCCGCC	NFYB	TCCCCGGCCAATCGG
SOX10	CGGACAAAGAC	SP2	CTCCCGCCCCCTCGA	MEIS2	CTGACAGC
SOX3	TCTTTGTCCG	TEAD2	CCCCAGTCCTGCA	RUNX1	CGCTGGGGCTT
SOX6	TCTTTGTCCG	TFDP1	AGGCGGGAATT	E2F4	GGGCGGGAGCA
TFDP1	GCGCGGGAATT	E2F6	GGGCGGGAGGC	MAFG	GATGAC

TF, transcription factor; motif, DNA sequence of target species which is predicted to be bound by the binding protein.