Serum Clusterin: A Potential Marker for Assessing the Clinical Severity and Short-Term Prognosis of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure

Table 4

Comparison of the area under the receiver operating characteristic curve, sensitivity, and specificity by the receiver operating characteristic curve for identifying hepatitis B virus-related acute-on-chronic liver failure.

Variable	AUC	95% CI	Cutoff value	Sensitivity	Specificity
PTA (%)	0.975	(0.000, 0.050)	40%	98.4%	65.8%
INR	0.976	(0.954, 0.998)	1.5	94.4%	88.9%
Total bilirubin (mg/dL)	0.888	(0.828, 0.948)	5.0	94.8%	69.8%
Clusterin (μg/mL)	0.964	(0.011, 0.061)	105	93.7%	90.7%

Abbreviations: AUC: area under the receiver operating characteristic curve; PTA: prothrombin activity; INR: international normalized ratio; CI: confidence intervals.