C-reactive Protein/Albumin Ratio and Acute Kidney Injury after Radical Cystectomy among Elderly Patients: A Propensity Score-Matched Analysis

Table 3

Univariate and multivariate logistic regression analyses of risk factors for acute kidney injury after radical cystectomy among elderly patients.

Variables	Univariate analysis		Multivariate analysis
	OR (95% CI)	value	OR (95% CI)	value
Sex (female)	0.559 (0.293–1.065)	0.077
Age	1.029 (0.983–1.078)	0.221
Body mass index	1.001 (0.931–1.077)	0.975
ASA physical status
≤2	1.000
3	1.064 (0.556–2.034)	0.852
Diabetes mellitus	0.831 (0.480–1.439)	0.508
Hypertension	0.713 (0.452–1.125)	0.146
Coronary artery disease	1.771 (0.799–3.925)	0.159
Cerebrovascular accident	0.472 (0.132–1.693)	0.249
COPD	1.509 (0.559–4.076)	0.417
Tumor stage
1	1.000
2	0.784 (0.364–1.687)	0.533
3	1.042 (0.442–2.456)	0.926
4	0.917 (0.354–2.375)	0.858
Tumor grade
2	1.000
3	0.947 (0.232–3.859)	0.939
Neoadjuvant chemotherapy	0.612 (0.344–1.089)	0.095
White blood cells	1.091 (1.003–1.186)	0.042
Hemoglobin	0.804 (0.710–0.910)	0.001
eGFR	0.989 (0.975–1.003)	0.135
Uric acid	1.016 (0.874–1.181)	0.837
CRP/albumin ratio	20.398 (6.379–65.227)	<0.001	21.747 (6.506–72.683)	<0.001
Operation duration	1.001 (0.999–1.003)	0.313
Crystalloid amount	1.001 (0.991–1.011)	0.826
6% hydroxyethyl starch amount	1.054 (1.020–1.089)	0.002	1.053 (1.014–1.093)	0.007
Red blood cell transfusion	2.086 (1.292–3.370)	0.003
Estimated blood loss	1.000 (1.000–1.001)	0.475
Intraoperative hypotension	1.146 (0.596–2.205)	0.683
Urinary diversion type
Ileal conduit	1.000
Ileal neobladder	0.555 (0.349–0.882)	0.013
Postoperative urinary infection	1.018 (0.592–1.751)	0.948
Postoperative urinary tract obstruction	0.000 (0.000–0.000)	>0.999
Postoperative NSAID use	1.422 (0.902–2.241)	0.130

OR: odds ratio; CI: confidence interval; ASA: American Society of Anesthesiologists; COPD: chronic obstructive pulmonary disease; eGFR: estimated glomerular filtration rate; CRP: C-reactive protein; NSAID: nonsteroidal anti-inflammatory drug. Multivariate logistic regression analysis included white blood cells, hemoglobin, CRP/albumin ratio, 6% hydroxyethyl starch amount, red blood cell transfusion, and urinary diversion type from the univariate logistic regression analysis.