Research Article

Evaluation of Altered Glutamatergic Activity in a Piglet Model of Hypoxic-Ischemic Brain Damage Using 1H-MRS

Figure 3

EAAT2 protein levels in the basal ganglia before (control) and after HI injury (400x magnification). Scale . (a–d) Representative figures of EAAT2 IHC staining in the control group and in 6 h, 12 h, and 72 h HI subgroups. (e) Changes in the average OD of EAAT2 protein. During early HI, EAAT2 protein level slightly decreased compared with the control; subsequently, it tended to increase and then decrease over time after HI injury. EAAT2: excitatory amino acid transporter 2; IHC: immunohistochemical; OD: optical density. Error bars represent the standard deviation values (/group). compared with the control group.
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