CD82 Suppresses ADAM17-Dependent E-Cadherin Cleavage and Cell Migration in Prostate Cancer

Figure 1

The expression of CD82 in PCa tissues and cell lines. (a) Immunohistochemical assay was applied to detect the expressions of CD82 in normal prostate tissues, prostate cancers, and matched adjacent normal tissues. Quantification of CD82 staining was shown in cancer and matched adjacent tissue and in cancers with different Gleason scores (N: matched adjacent normal tissue, T: prostate cancer). (b) Real-time PCR (left) and Western blot (right) showed the expressions of CD82 in prostate normal epithelia cells RWPE-1, benign prostatic hyperplasia cell BPH-1, and various PCa cell lines. Error bars indicate s.d. from at least two technical replicates.

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