Research Article
CD82 Suppresses ADAM17-Dependent E-Cadherin Cleavage and Cell Migration in Prostate Cancer
Figure 2
The effects of CD82 on PCa cell migration. PC-3 was transfected with control vector, pcDNA3.0-CD82#1, and pcDNA3.0-CD82#2, while C4-2 was transfected with scramble negative control, siRNA-CD82#789, and siRNA-CD82#1162, and the expressions of CD82 were determined by (a) real-time PCR and (b) Western blot. (c) The properties of cell migration were identified by transwell assay with quantification results. (d) Cell growth properties were detected by tetrazolium-based assay in PC-3 with CD82 overexpression and C4-2 with CD82 knockdown. . Error bars indicate s.d. from at least two technical replicates.
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