CD82 Suppresses ADAM17-Dependent E-Cadherin Cleavage and Cell Migration in Prostate Cancer

Figure 3

CD82 inhibited the cleavage of E-cadherin in PCa cells. In (a) PC-3 with CD82 overexpression and (b) C4-2 with CD82 knockdown, Western blot detected the full-length E-cadherin (FL) and cytoplasmic E-cadherin fragments (CTF) (left), and the ratios of shedding fragments to full-length E-cadherin were quantified (right).

(a)

(b)