Research Article

Selected Metal Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases as Potential Biomarkers for Tubulointerstitial Fibrosis in Children with Unilateral Hydronephrosis

Table 1

Characteristics of study and control groups.

ParameterStudy group median (range) and number of patientsControl group

Number of patients4521
Gender (male/female)31/1416/5
Age (years)11.0 (2-17)12.3 (3-17)
GFR (ml/min/1.73 m2)126.3 (97-162)139 (102-145)
Number of patients in groups A/B/C25/11/9
Number of patients with obstructive nephropathy28/45 (62.2%)
Number of patients with proteinuria10/45 (22.2%)
Protein/creatinine ratio (mg/mg)0.24 (0.21-0.4)0.09 (0-0.15)