Review Article

Diagnostic Value of Neutrophil-Lymphocyte Ratio for Predicting the Severity of Acute Pancreatitis: A Meta-Analysis

Table 2

Subgroup analysis stratified by population, sample, and publication year.

CategoryNo. of studiesSEN (95% CI)SPE (95% CI)NLR (95% CI)PLR (95% CI)DOR (95% CI)AUC (95% CI)

Population
 Asian778% (71%-84%)68% (54%-80%)0.32 (0.21-0.47)2.5 (1.6-3.9)8 (4-17)0.81 (0.77-0.84)
Sample
 >100778% (70%-84%)66% (55%-75%)0.33 (0.23-0.49)2.3 (1.6-3.2)7 (4-13)0.80 (0.76-0.83)
Publication year
 >2015878% (70%-84%)0.69 (0.58-0.79)0.32 (0.23-0.46)2.5 (1.8-3.6)8 (4-15)0.81 (0.77-0.84)
Overall1079% (73%-84%)0.71 (0.59-0.80)0.30 (0.21-0.41)2.7 (1.8-4.0)9 (5-18)0.82 (0.78-0.85)
Outliers excluded981% (76%-85%)0.72 (0.60-0.82)0.26 (0.20-0.34)2.9 (2.0-4.4)11 (6-21)0.82 (0.79-0.85)

SEN: sensitivity; SPE: specificity; NLR: negative likelihood ratio; PLR: positive likelihood ratio; DOR: diagnostic odds ratio; AUC: area under the receiver operating characteristic curve.