Research Article

APOA-5 Genetic Variant rs662799: Role in Lipid Changes and Insulin Resistance after a Mediterranean Diet in Caucasian Obese Subjects

Table 2

Biochemical parameters ().

ParametersTT ()TC+CC ()
Basal3 monthsBasal3 months values
-Time TT
-Basal genotype
-Time TC+CC
-3 months genotype

Glucose (mg/dL)


Total cholesterol (mg/dL)$$


LDL-cholesterol (mg/dL)##


HDL-cholesterol (mg/dL)


Triglycerides (mg/dL)++


Insulin (mUI/L)&


HOMA-IR


CRP



HOMA-IR: homeostasis model assessment; CRP: C reactive protein. Statistical differences , in each genotype group (total cholesterol$, LDL-cholesterol#, insulin&, HOMA IR) (triglyceride between genotypes+). First : significance of dietary intervention after 3 months in TT genotype; second : significance between TT genotypes vs. TC+CC baseline values; third : significance of dietary intervention after 12 weeks in TC+CC genotype; fourth : significance between TT genotypes vs. TC+CC posttreatment values.