STAT1-Induced Upregulation lncRNA LINC00958 Accelerates the Epithelial Ovarian Cancer Tumorigenesis by Regulating Wnt/<i>β</i>-Catenin Signaling

<div>STAT1 is bound to the promoter region of LINC00958 and activated its transcription. (a) “GEPIA” showed the expression trend of several transcription factors. (b) The positive associations between LINC00958 and STAT1 levels. (c) JASPAR was used for the determination of STAT1 binding site prediction in the LINC00958 promoter region. (d) Expression levels of LINC00958 in SKOV3 cells after knockdown of STAT1 or overexpression of STAT1. (e) The levels of LINC00958 in SKOV3 cells after transfection. (f) ChIP assays were conducted to confirm the interaction between STAT1 and the LINC00958 promoter. 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Disease Markers

fig4

Figure 4

Figure 4: STAT1-Induced Upregulation lncRNA LINC00958 Accelerates the Epithelial Ovarian Cancer Tumorigenesis by Regulating Wnt/<i>β</i>-Catenin Signaling 

Disease Markers

STAT1-Induced Upregulation lncRNA LINC00958 Accelerates the Epithelial Ovarian Cancer Tumorigenesis by Regulating Wnt/β-Catenin Signaling

Figure 4