Cancer-Derived Exosomal miR-651 as a Diagnostic Marker Restrains Cisplatin Resistance and Directly Targets ATG3 for Cervical Cancer

Figure 2

miR-651 expression and its functions on cisplatin resistance, proliferation, and apoptosis in cervical cancer cells. (a) Comparison of miR-651 expression in HcerEpic, C33A, HT-3, HeLa/S, and HeLa/DDP cell lines. (b) Verification of miR-651 expression in HeLa/S and HeLa/DDP cells with NC or miR-651 mimic transfection. (c, d) Determination of the IC50 values of cisplatin on NC- or miR-651 mimic-induced HeLa/S as well as HeLa/DDP cells. (e–h) Flow cytometry for apoptosis rates of HeLa/S and HeLa/DDP cells under treatment with NC or miR-651 mimics. (i–l) The colony formation number of NC- or miR-651 mimic-induced HeLa/S as well as HeLa/DDP cells. ; ; ; .

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