Disease Markers

Research Article

Epigenetic Silencing of SOX15 Is Controlled by miRNAs rather than Methylation in Papillary Thyroid Cancer

Table 4

Mean (±SD) expression values of miRNA-182, miRNA-183, miRNA-96, and miRNA-375 in tumor and noncancerous tissues.


		Target Ct	Reference Ct	∆Ct	∆∆Ct	2^-∆∆Ct

miRNA-182	Tumor				-1.64	3.11	<0.001
miRNA-182	Noncancerous				0	1	<0.001
miRNA-183	Tumor				-1.27	2.41	0.003
miRNA-183	Noncancerous				0	1	0.003
miRNA-375	Tumor				-2.04	4.1	0.001
miRNA-375	Noncancerous				0	1	0.001
miRNA-96	Tumor				0.24	0.85	0.628
miRNA-96	Noncancerous				0	1	0.628

Statistical analyses were performed by paired sample -test. Statistical analyses were performed by the Wilcoxon Signed Rank Test. SD: standard deviation.