Research Article

Urinary Matrix Metalloproteinase-9 and Nephrin in Idiopathic Membranous Nephropathy: A Cross-Sectional Study

Table 1

Comparison of demographic and basic clinical characteristics between patients and healthy controls.

ParametersHealthy controls ()IMN patients () value

Sex (male/female)45/2567/400.475
Age (years)0.277
Diastolic blood pressure (mm/Hg)77.00 (67.00-87.00)80.00 (70.00-90.00)0.020
Systolic blood pressure (mm/Hg)121.00 (113.00-133.00)123.00 (123.00-133.00)0.035
Fasting blood glucose (mmol/l)0.379
Serum protein(g/l)74.35 (71.60-76.55)46.20 (38.10-52.60)0.015
Serum albumin (g/l)47.20 (45.27-48.62)25.40 (19.60-33.00)0.041
Urine protein (mg/μmol Cr)3.26 (1.93-4.91)372.18 (181.12-734.65)0.021
Serum cystatin C (mg/l)0.011
Serum creatinine (μmol/l)0.370
Serum uric acid (μmol/l)0.023
Serum urea (mmol/l)0.033
eGFR (ml/min/m2)104.60 (90.25-118.69)104.82 (96.76-112.20)0.798

IMN: idiopathic membranous nephropathy; eGFR: estimated glomerular filtration rate.