lncRNA LINC00355 Acts as a Novel Biomarker and Promotes Glioma Biological Activities via the Regulation of miR-1225/FNDC3B

<div>LINC00355 sponged miR-1225 in glioma cells. (a) Subcellular fractionation assay clarified the subcellular location of LINC00355 in U251 cells. (b) The heat map of differentially expressed miRNAs in GSE90603 data. (c) The intersection between the downregulated miRNAs in glioma tumor tissues and the predicting target miRNAs using miRDB program. (d) The relative expression of miR-1225 in GSE90603 data. (e) The expressions of miR-1225 in 121 glioma tumor specimens. (f) CCK-8 assays. (g) miRDB program predicted the binding sites between LINC00355 and miR-1225. (h) Luciferase activity detection. 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Disease Markers

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Figure 4

Figure 4: lncRNA LINC00355 Acts as a Novel Biomarker and Promotes Glioma Biological Activities via the Regulation of miR-1225/FNDC3B 