The Prognostic Value of the Albumin to Gamma-Glutamyltransferase Ratio in Patients with Hepatocellular Carcinoma Undergoing Radiofrequency Ablation

Table 1

Demographics and clinical characteristics of patients in the training and validation cohorts.

	Total ()	Training cohort ()	Validation cohort ()	value
Gender				0.538
Male	306	219	87
Female	88	60	28
Age				0.726
TB (μmol/L)				0.173
ALT (U/L)				0.117
PT				0.564
ALB				0.793
AFP				0.275
γ-GT (U/L)				0.363
Etiology				0.544
HBV infection	311	224	87
HCV infection	13	8	5
Other	70	47	23
Liver cirrhosis				0.743
Yes	259	182	77
No	135	97	38
AKP (U/L)				0.236
AGR				0.806
CP grade				0.874
A	394	277	114
B	3	2	1
AGR				0.403
1	232	168	64
2	162	111	51
γ-GT (U/L)				0.719
≤50	195	140	55
>50	199	139	60
Tumor size (cm)				0.253
≤3	322	232	90
3-5	72	47	25
Tumor number				0.397
Single	315	220	95
Multiple	79	59	20
AJCC TNM-8				0.137
Ia	180	133	47
Ib	135	87	48
II	79	59	20
ALBI				0.264
1	225	166	59
2	164	109	55
3	5	4	1

Abbreviations: AGR: albumin to gamma-glutamyltransferase ratio; TB: total bilirubin; ALT: alanine aminotransferase; PT: prothrombin time; ALB: albumin; AFP: alfa-fetoprotein; γ-GT: γ-glutamyl transpeptidase; HBV: hepatitis B virus; HCV: hepatitis C virus; AKP: alkaline phosphatase; CP grade: Child-Pugh grade; AJCC TNM-8: the 8th edition of American Joint Committee on Cancer TNM staging system; ALBI grade: albumin-bilirubin grade. Statistically significant.