Cox-2 Antagonizes the Protective Effect of Sevoflurane on Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis through Inhibiting the Akt Pathway

<div>Overexpression of Cox-2 suppressed cardioprotective role of SEV. The mRNA (a) and protein level (b) of Cox-2 in H9c2 cells transfected with NC or Cox-2 OE. Cell viability (c) and LDH release (d) in H9c2 cells of NC group, H/R group, H/R + SEV group, and H/R + SEV + Cox-2 group.</div>

Disease Markers

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Figure 3

Figure 3: Cox-2 Antagonizes the Protective Effect of Sevoflurane on Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis through Inhibiting the Akt Pathway 

Figure 3 | Cox-2 Antagonizes the Protective Effect of Sevoflurane on Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis through Inhibiting the Akt Pathway 