Diagnostic, Prognostic, Predictive, and Monitoring Role of Neutrophil CD11b and Monocyte CD14 in Neonatal Sepsis

Figure 2

nCD11b%, nCD11b MFI, mCD14%, and mCD14 MFI box blots for the healthy controls, diseased controls, and group of patients with sepsis. nCD11b%: no significant difference in sepsis neonates (median (IQR): 99.05 (97.1-99.7)%) when compared to either the healthy controls (median (IQR): 96.95 (95.525-98.1)%) and the diseased controls (median (IQR): 97.35 (95.5-98.5)%); additionally, no significant difference was found upon comparing healthy and diseased controls together (). nCD11b MFI: no significant difference was documented when the sepsis group (median (IQR): 5.09 (3.7525-7)) was compared to both the healthy controls (median (IQR): 5.555 (4.4575- 6.22)) and the diseased controls (median (IQR): 5.905 (4.625-6.4525)), and no significant difference was found upon comparing healthy and diseased controls (). mCD14%: no significant difference was documented when the sepsis group (median (IQR): 82.7 (58.88-90.7)%) was compared to both the healthy controls (median (IQR): 84.15 (80.075-89.05)%) and the diseased controls (median (IQR): 85.7 (79.1-90.9)%), and no significant difference was found upon comparing healthy and diseased controls (). mCD14 MFI: it was significantly elevated () in the sepsis group (median (IQR): 10.8 (9.315-13.2)) when compared to the healthy controls (median (IQR): 7.8 (6-8.23)), while no significant difference was reported () when the diseased controls (median (IQR): 10.015 (7.7725-11.2)) were compared with the sepsis group. Also, a statistically significant difference was found when healthy and pathological controls were compared together () being higher in the diseased controls.