Research Article
Diagnostic, Prognostic, Predictive, and Monitoring Role of Neutrophil CD11b and Monocyte CD14 in Neonatal Sepsis
Table 2
Comparative statistical analysis between the group of sepsis and each of the control groups separately.
| | Healthy controls | Diseased controls | Sepsis group | | | | Median (IQR) | Median (IQR) | Median (IQR) | Between healthy controls and sepsis patients | Between diseased controls and sepsis patients |
| | Hb | 17 (13.75-18.85) | 12.85 (10.325-17.8) | 12.4 (10.7-14.7) | <0.001 | 0.259 | | TLC | 14.3 (12-17.25) | 12.7 (9.05-17) | 13.3 (8.45-19.1) | 0.157 | 0.648 | | ANC | 5.1 (3.4-11) | 4 (2.7-9.6025) | 6.5 (4.4-11.8) | 0.205 | 0.007 | | ALC | 5.6 (4.1-7.5) | 5.7 (5-6.85) | 4 (2.55-6.9) | 0.008 | 0.001 | | AMC | 1.4 (0.9-2) | 1 (0.75-1.5) | 1.2 (0.7-2) | 0.173 | 0.299 | | PLT | 213 (145-292.25) | 348.5 (226.25-408.5) | 203 (98.25-307.75) | 0.359 | <0.001 | | hs-CRP | 5 (5-6) | 5 (5-5) | 12 (6-39.25) | <0.001 | <0.001 | | nCD11b% | 96.95 (95.525-98.1) | 97.35 (95.5-98.5) | 99.05 (97.1-99.7) | 0.446 | 0.345 | | nCD11b MFI | 5.555 (4.4575-6.22) | 5.905 (4.625-6.4525) | 5.09 (3.7525-7) | 0.619 | 0.262 | | mCD14% | 84.15 (80.075-89.05) | 85.7 (79.1-90.9) | 82.7 (58.88-90.7) | 0.435 | 0.11 | | mCD14 MFI | 7.8 (6-8.23) | 10.015 (7.7725-11.2) | 10.8 (9.315-13.2) | <0.001 | 0.157 |
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Values are presented as median (IQR). Hb: hemoglobin (g/dL); TLC: total leukocyte count (×10 9/L); ANC: absolute neutrophil count (×10 9/L); ALC: absolute lymphocyte count (×10 9/L); AMC: absolute monocyte count (×10 9/L); PLT: platelet (×10 9/L); hs-CRP: highly sensitive CRP (mg/L); nCD11b%: neutrophil CD11b%; nCD11b MFI: nCD11b mean fluorescence intensity; mCD14%: monocyte CD14%; mCD14 MFI: mCD14 mean fluorescence intensity; : a probability value. |
