Research Article
Diagnostic, Prognostic, Predictive, and Monitoring Role of Neutrophil CD11b and Monocyte CD14 in Neonatal Sepsis
Table 9
The predictive validity results for the studied sepsis markers arranged in ascending order in terms of their sensitivities.
| | Cutoff | TN | FP | TP | FN | Specificity (%) | Sensitivity (%) | NPV (%) | PPV (%) | Eff. (%) | AUC |
| nCD11b% | 98.5 | 29 | 20 | 11 | 11 | 59.2 | 50.0 | 72.5 | 35.5 | 56.3 | 0.504 | hs-CRP | 1.4 | 40 | 39 | 20 | 19 | 50.6 | 51.3 | 67.8 | 33.9 | 50.8 | 0.456 | mCD14% | 75.3 | 35 | 13 | 12 | 10 | 72.9 | 54.5 | 77.8 | 48.0 | 67.1 | 0.594 | nCD11b MFI | 4.64 | 34 | 15 | 13 | 9 | 69.4 | 59.1 | 79.1 | 46.4 | 66.2 | 0.620 | ANC | 6.2 | 40 | 31 | 22 | 15 | 56.3 | 59.5 | 72.7 | 41.5 | 57.4 | 0.383 | mCD14 MFI | 9.97 | 26 | 11 | 10 | 5 | 70.3 | 66.7 | 83.9 | 47.6 | 69.2 | 0.673 | mCD14 MFI & mCD14% | CD14 MFI at 9.97 & CD14% at 44.7% | 36 | 1 | 10 | 5 | 97.3 | 66.7 | 87.8 | 90.9 | 88.5 | 0.846 |
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Eff.: efficacy; NPV: negative predictive value; PPV: positive predicted value; TP: true positive; TN: true negative; FP: false positive; FN: false negative.
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